Published by admin on 16 May 2008
One-pot cascade reaction of Suzuki-Miyaura coupling/aldol condensation can be a mild, simple, and efficient method for the synthesis of highly functionalized phenanthrenes.
Published by admin on 14 May 2008
The palladium-catalyzed four-component cross-coupling of imines, chloroformates, organostannane reagents, and carbon monoxide can be utilized to generate ketocarbamates (1), which are amenable to cyclization to generate imidazolones. Considering the mild conditions (1 atm of carbon monoxide, room temperature) and simple building blocks employed, this provides straightforward access to these heterocycles.
